| 1751 | Trinity School | 1,675 pupils | Academy · Day · 6th | Carlisle, North West | — |
| 1752 | Kettlethorpe High School | 1,672 pupils | State · Day | Wakefield, Yorkshire and the Humber | — |
| 1753 | High Storrs School | 1,668 pupils | Academy · Day · 6th | Sheffield, Yorkshire and the Humber | — |
| 1754 | Alderbrook School | 1,667 pupils | Academy · Day · 6th | Solihull, West Midlands | — |
| 1755 | The Regis School | 1,665 pupils | Academy · Day · 6th | West Sussex, South East | — |
| 1756 | Queens' School | 1,660 pupils | Academy · Day · 6th | Bushey, East of England | — |
| 1757 | Samuel Whitbread Academy | 1,660 pupils | Academy · Day · 6th | Shefford, East of England | — |
| 1758 | Oasis Academy Shirley Park | 1,659 pupils | Academy · Day · 6th | Croydon, London | — |
| 1759 | Claremont High School | 1,657 pupils | Academy · Day · 6th | Harrow, London | — |
| 1760 | Cotham School | 1,655 pupils | Academy · Day · 6th | Bristol, South West | — |
| 1761 | Rodillian Academy | 1,654 pupils | Academy · Day · 6th | Wakefield, Yorkshire and the Humber | — |
| 1762 | Newquay Tretherras | 1,653 pupils | Academy · Day · 6th | Newquay, South West | — |
| 1763 | Arthur Mellows Village College | 1,651 pupils | Academy · Day · 6th | Peterborough, East of England | — |
| 1764 | Beaumont School | 1,651 pupils | Academy · Day · 6th | St Albans, East of England | — |
| 1765 | Mill Hill County High School | 1,651 pupils | Academy · Day · 6th | London, London | — |
| 1766 | Highlands School | 1,650 pupils | State · Day · 6th | London, London | — |
| 1767 | Ely College | 1,649 pupils | Academy · Day · 6th | Ely, East of England | — |
| 1768 | Stoke Newington School and Sixth Form | 1,647 pupils | State · Day · 6th | London, London | — |
| 1769 | Whalley Range 11-18 High School | 1,647 pupils | Academy · Day · 6th | Manchester, North West | — |
| 1770 | Calthorpe Park School | 1,644 pupils | State · Day | Fleet, South East | — |
| 1771 | Didcot Girls' School | 1,643 pupils | Academy · Day · 6th | Didcot, South East | — |
| 1772 | Holly Lodge High School College of Science | 1,643 pupils | State · Day · 6th | Smethwick, West Midlands | — |
| 1773 | Cardinal Newman Catholic School A Specialist Science College | 1,641 pupils | Academy · Day · 6th | Luton, East of England | — |
| 1774 | Wymondham High Academy | 1,639 pupils | Academy · Day · 6th | Wymondham, East of England | — |
| 1775 | Otley Prince Henry's Grammar School Specialist Language College | 1,638 pupils | Academy · Day · 6th | Otley, Yorkshire and the Humber | — |