| 376 | Birchwood Community High School | 889 pupils | Academy · Day | Warrington, North West | — |
| 377 | Richard Rose Morton Academy | 883 pupils | Academy · Day · 6th | Carlisle, North West | — |
| 378 | Shevington High School | 878 pupils | State · Day | Wigan, North West | — |
| 379 | St Cuthbert's Catholic High School | 876 pupils | State · Day | St Helens, North West | — |
| 380 | Netherhall School | 874 pupils | State · Day · 6th | Maryport, North West | — |
| 381 | Ashton Community Science College | 868 pupils | State · Day | Preston, North West | — |
| 382 | Up Holland High School | 861 pupils | Academy · Day | Wigan, North West | — |
| 383 | West Hill School | 853 pupils | Academy · Day | Stalybridge, North West | — |
| 384 | Archbishop Temple Church of England High School | 837 pupils | State · Day | Preston, North West | — |
| 385 | Stanley High School | 836 pupils | Academy · Day | Southport, North West | — |
| 386 | Saint Aidan's Church of England High School | 835 pupils | State · Day | Poulton-le-Fylde, North West | — |
| 387 | St Bede's Catholic High School, Lytham | 829 pupils | State · Day | Lytham St Annes, North West | — |
| 388 | Dowdales School | 827 pupils | State · Day | Dalton-in-Furness, North West | — |
| 389 | St Damian's RC Science College | 827 pupils | State · Day | Ashton-under-Lyne, North West | — |
| 390 | The Oldershaw School | 825 pupils | Academy · Day · 6th | Wallasey, North West | — |
| 391 | St James' Catholic High School | 824 pupils | State · Day | Cheadle, North West | — |
| 392 | Hutton Church of England Grammar School | 823 pupils | State · Day · 6th | Preston, North West | — |
| 393 | Outwood Academy Haydock | 819 pupils | Academy · Day | St. Helens, North West | — |
| 394 | St Mary's Catholic High School | 817 pupils | State · Day | Leyland, North West | — |
| 395 | All Saints Catholic College | 816 pupils | Academy · Day | Dukinfield, North West | — |
| 396 | King's Leadership Academy Warrington | 808 pupils | Free School · Day | Warrington, North West | — |
| 397 | The Catholic High School, Chester | 808 pupils | Academy · Day · 6th | Chester, North West | — |
| 398 | Corpus Christi Catholic High School | 807 pupils | State · Day | Preston, North West | — |
| 399 | Harrytown Catholic High School | 803 pupils | State · Day | Stockport, North West | — |
| 400 | The Hollins | 794 pupils | Academy · Day | Accrington, North West | — |