| 51 | North Cestrian School Period 202425 | 54.2 | Free School · Day | Altrincham, North West | — |
| 52 | Wade Deacon High School Period 202425 | 54.0 | Academy · Day | Widnes, North West | Outstanding |
| 53 | Chorlton High School Period 202425 | 54.0 | Academy · Day | Manchester, North West | — |
| 54 | Canon Slade School Period 202425 | 53.9 | Academy · Day · 6th | Bolton, North West | — |
| 55 | St Patrick's RC High School Period 202425 | 53.8 | State · Day | Manchester, North West | Good |
| 56 | Bishop Heber High School Period 202425 | 53.8 | State · Day · 6th | Malpas, North West | Good |
| 57 | The Belvedere Academy Period 202425 | 53.8 | Academy · Day · 6th | Liverpool, North West | — |
| 58 | The Bishops' Blue Coat Church of England High School Period 202425 | 53.8 | Academy · Day · 6th | Chester, North West | Good |
| 59 | St James's Church of England High School Period 202425 | 53.5 | Academy · Day | Bolton, North West | Good |
| 60 | The Fallibroome Academy Period 202425 | 53.4 | Academy · Day · 6th | Macclesfield, North West | Good |
| 61 | Eden Boys' Leadership Academy, Manchester Period 202425 | 53.1 | Free School · Day · 6th | Manchester, North West | Good |
| 62 | Essa Academy Period 202425 | 53.0 | Academy · Day | Bolton, North West | Good |
| 63 | Poynton High School Period 202425 | 53.0 | Academy · Day · 6th | Stockport, North West | — |
| 64 | Eden Boys' School, Bolton Period 202425 | 53.0 | Free School · Day | Bolton, North West | — |
| 65 | John Ruskin School Period 202425 | 52.9 | State · Day | Coniston, North West | Good |
| 66 | Penwortham Girls' High School Period 202425 | 52.9 | State · Day | Preston, North West | Outstanding |
| 67 | Fairfield High School for Girls Period 202425 | 52.7 | Academy · Day | Manchester, North West | Good |
| 68 | Priestnall School Period 202425 | 52.6 | Academy · Day | Stockport, North West | Requires Improvement |
| 69 | Levenshulme High School Period 202425 | 52.5 | Academy · Day | Manchester, North West | — |
| 70 | Balshaw's Church of England High School Period 202425 | 52.3 | State · Day | Leyland, North West | Good |
| 71 | Ashton-on-Mersey School Period 202425 | 52.1 | Academy · Day · 6th | Sale, North West | — |
| 72 | Whalley Range 11-18 High School Period 202425 | 52.1 | Academy · Day · 6th | Manchester, North West | — |
| 73 | Keswick School Period 202425 | 52.1 | Academy · Boarding · 6th | Keswick, North West | Outstanding |
| 74 | Alsager School Period 202425 | 51.9 | Academy · Day · 6th | Stoke-on-Trent, North West | Good |
| 75 | Cockermouth School Period 202425 | 51.9 | Academy · Day · 6th | Cockermouth, North West | — |