| 1 | Pate's Grammar School Period 202122 | 52.1 | Grammar · Day · 6th | Cheltenham, South West | Outstanding |
| 2 | Colyton Grammar School Period 202122 | 50.0 | Grammar · Day · 6th | Colyton, South West | Outstanding |
| 3 | St John's Marlborough Period 202324 | 48.1 | Academy · Day · 6th | Marlborough, South West | — |
| 4 | Newquay Tretherras Period 202324 | 48.1 | Academy · Day · 6th | Newquay, South West | — |
| 5 | Camborne Science and International Academy Period 202122 | 47.9 | Academy · Day · 6th | Camborne, South West | Good |
| 6 | Bournemouth School for Girls Period 202122 | 47.8 | Grammar · Day · 6th | Bournemouth, South West | Outstanding |
| 7 | The Clarendon Academy Period 202223 | 47.5 | Academy · Day · 6th | Trowbridge, South West | — |
| 8 | The Blue School Period 202324 | 47.5 | Academy · Day · 6th | Wells, South West | — |
| 9 | Poole Grammar School Period 202425 | 46.9 | Grammar · Day · 6th | Poole, South West | — |
| 10 | The Bourne Academy Period 202324 | 46.8 | Academy · Day · 6th | Bournemouth, South West | Good |
| 11 | Huish Episcopi Academy Period 202425 | 46.8 | Academy · Day · 6th | LANGPORT, South West | Inadequate |
| 12 | Sir Thomas Rich's School Period 202122 | 46.8 | Grammar · Day · 6th | Gloucester, South West | Good |
| 13 | The Blandford School Period 202122 | 46.4 | State · Day · 6th | Blandford Forum, South West | Good |
| 14 | Torquay Girls' Grammar School Period 202122 | 46.1 | Grammar · Day · 6th | Torquay, South West | Outstanding |
| 15 | Bishop Wordsworth's Church of England Grammar School Period 202122 | 46.1 | Grammar · Day · 6th | Salisbury, South West | Outstanding |
| 16 | Budehaven Community School Period 202122 | 45.8 | State · Day · 6th | Bude, South West | Good |
| 17 | Stroud High School Period 202122 | 45.8 | Grammar · Day · 6th | Stroud, South West | Outstanding |
| 18 | The Purbeck School Period 202122 | 45.7 | Academy · Day · 6th | Wareham, South West | — |
| 19 | Churston Ferrers Grammar School Academy Period 202223 | 45.5 | Grammar · Day · 6th | Brixham, South West | Good |
| 20 | Devizes School Period 202122 | 45.4 | Academy · Day · 6th | Devizes, South West | — |
| 21 | Sir John Hunt Community Sports College Period 202324 | 45.0 | State · Day · 6th | Plymouth, South West | Good |
| 22 | SGS Berkeley Green UTC Period 202122 | 45.0 | Free School · Day · 6th | Berkeley, South West | Good |
| 23 | Lytchett Minster School Period 202223 | 44.6 | State · Day · 6th | Poole, South West | — |
| 24 | Frome Community College Period 202324 | 44.4 | Academy · Day · 6th | Frome, South West | — |
| 25 | Ivybridge Community College Period 202223 | 44.4 | Academy · Day · 6th | Ivybridge, South West | Good |