| 51 | Bournemouth School Period 202122 | 42.2 | Grammar · Day · 6th | Bournemouth, South West | Outstanding |
| 52 | Somervale Secondary School Period 202223 | 42.0 | Academy · Day · 6th | Radstock, South West | — |
| 53 | Torquay Academy Period 202122 | 42.0 | Academy · Day · 6th | Torquay, South West | — |
| 54 | Chew Valley School Period 202122 | 41.8 | Academy · Day · 6th | Bristol, South West | — |
| 55 | The John of Gaunt School Period 202122 | 41.7 | Academy · Day · 6th | Trowbridge, South West | — |
| 56 | Newent Community School and Sixth Form Centre Period 202122 | 41.7 | Academy · Day · 6th | Newent, South West | — |
| 57 | Matravers School Period 202122 | 41.6 | State · Day · 6th | Westbury, South West | Good |
| 58 | Plymstock School Period 202122 | 41.5 | Academy · Day · 6th | Plymouth, South West | Good |
| 59 | The Bishop of Winchester Academy Period 202122 | 41.5 | Academy · Day · 6th | Bournemouth, South West | Good |
| 60 | Launceston College Period 202425 | 41.4 | Academy · Day · 6th | Launceston, South West | Good |
| 61 | Malmesbury School Period 202122 | 41.3 | Academy · Day · 6th | Malmesbury, South West | Outstanding |
| 62 | Bideford College Period 202122 | 41.3 | Academy · Day · 6th | Bideford, South West | Good |
| 63 | South Dartmoor Community College Period 202324 | 41.3 | Academy · Day · 6th | Ashburton, South West | — |
| 64 | Ribston Hall High School Period 202122 | 41.3 | Grammar · Day · 6th | Gloucester, South West | — |
| 65 | Melksham Oak Community School Period 202122 | 41.2 | Academy · Day · 6th | Melksham, South West | Good |
| 66 | Writhlington School Period 202122 | 41.2 | Academy · Day · 6th | Radstock, South West | Good |
| 67 | St Laurence School Period 202122 | 41.0 | Academy · Day · 6th | Bradford-on-Avon, South West | — |
| 68 | Abbeywood Community School Period 202122 | 40.9 | Academy · Day · 6th | Bristol, South West | — |
| 69 | Lipson Co-operative Academy Period 202122 | 40.9 | Academy · Day · 6th | Plymouth, South West | Good |
| 70 | Tewkesbury Academy Period 202122 | 40.7 | Academy · Day · 6th | Tewkesbury, South West | — |
| 71 | St Mary Redcliffe and Temple School Period 202122 | 40.7 | State · Day · 6th | Bristol, South West | — |
| 72 | The Gryphon School Period 202122 | 40.7 | Academy · Day · 6th | Sherborne, South West | — |
| 73 | The Woodroffe School Period 202122 | 40.5 | State · Day · 6th | Lyme Regis, South West | Good |
| 74 | Treviglas Academy Period 202122 | 40.4 | Academy · Day · 6th | Newquay, South West | — |
| 75 | Marling School Period 202324 | 40.3 | Grammar · Day · 6th | Stroud, South West | — |