| 26 | Lydiard Park Academy Period 202122 | 44.3 | Academy · Day · 6th | Swindon, South West | — |
| 27 | The Cotswold Academy Period 202122 | 44.1 | Academy · Day · 6th | Cheltenham, South West | — |
| 28 | Torquay Boys' Grammar School Period 202122 | 43.9 | Grammar · Day · 6th | Torquay, South West | Good |
| 29 | Balcarras School Period 202122 | 43.9 | Academy · Day · 6th | Cheltenham, South West | — |
| 30 | Ralph Allen School Period 202122 | 43.7 | Academy · Day · 6th | Bath, South West | — |
| 31 | Katharine Lady Berkeley's School Period 202122 | 43.7 | Academy · Day · 6th | Wotton-under-Edge, South West | — |
| 32 | The King Alfred School an Academy Period 202122 | 43.6 | Academy · Day · 6th | Highbridge, South West | Good |
| 33 | Gordano School Period 202425 | 43.5 | Academy · Day · 6th | Bristol, South West | Good |
| 34 | Parkstone Grammar School Period 202122 | 43.5 | Grammar · Day · 6th | Poole, South West | — |
| 35 | St Edward's Roman Catholic/Church of England School, Poole Period 202122 | 43.3 | State · Day · 6th | Poole, South West | — |
| 36 | The Crypt School Period 202122 | 43.3 | Grammar · Day · 6th | Gloucester, South West | Outstanding |
| 37 | Corfe Hills School Period 202425 | 43.3 | Academy · Day · 6th | Broadstone, South West | Good |
| 38 | Devonport High School for Girls Period 202122 | 43.2 | Grammar · Day · 6th | Plymouth, South West | Good |
| 39 | Kingsbridge Academy Period 202122 | 43.2 | Academy · Day · 6th | Kingsbridge, South West | Good |
| 40 | Denmark Road High School Period 202122 | 43.0 | Grammar · Day · 6th | Gloucester, South West | Good |
| 41 | Saltash Community School Period 202425 | 42.8 | Academy · Day · 6th | Saltash, South West | — |
| 42 | Hardenhuish School Period 202122 | 42.8 | Academy · Day · 6th | Chippenham, South West | — |
| 43 | Ferndown Upper School Period 202425 | 42.7 | State · Day · 6th | Ferndown, South West | — |
| 44 | Bristol Cathedral Choir School Period 202122 | 42.6 | Academy · Day · 6th | Bristol, South West | Good |
| 45 | Kingdown School Period 202425 | 42.5 | Academy · Day · 6th | Warminster, South West | — |
| 46 | King Edward VI Community College Period 202425 | 42.5 | Academy · Day · 6th | Totnes, South West | — |
| 47 | South Wilts Grammar School Period 202122 | 42.3 | Grammar · Day · 6th | Salisbury, South West | Good |
| 48 | Bristol Free School Period 202122 | 42.3 | Free School · Day · 6th | Bristol, South West | Good |
| 49 | Churchill Academy & Sixth Form Period 202223 | 42.3 | Academy · Day · 6th | Winscombe, South West | — |
| 50 | Devonport High School for Boys Period 202122 | 42.3 | Grammar · Day · 6th | Plymouth, South West | Good |