| 1 | Prudhoe Community High School Period 202122 | 50.0 | Academy · Day · 6th | Prudhoe, North East | — |
| 2 | Whitley Bay High School Period 202122 | 48.9 | State · Day · 6th | Whitley Bay, North East | Outstanding |
| 3 | Cardinal Hume Catholic School, Gateshead Period 202122 | 48.2 | Academy · Day · 6th | Gateshead, North East | Outstanding |
| 4 | Conyers School Period 202122 | 45.8 | Academy · Day · 6th | Yarm, North East | — |
| 5 | Trinity Catholic College Period 202223 | 45.6 | Academy · Day · 6th | Middlesbrough, North East | — |
| 6 | St Robert of Newminster Catholic School and Sixth Form College, Washington Period 202223 | 45.0 | Academy · Day · 6th | Washington, North East | — |
| 7 | Ponteland High School Period 202425 | 45.0 | Academy · Day · 6th | Ponteland, North East | Good |
| 8 | Durham Johnston Comprehensive School Period 202122 | 44.9 | State · Day · 6th | Durham, North East | — |
| 9 | St Thomas More Catholic School, Blaydon Period 202122 | 44.1 | Academy · Day · 6th | Blaydon-on-Tyne, North East | Good |
| 10 | Egglescliffe School Period 202122 | 43.8 | Academy · Day · 6th | Stockton-on-Tees, North East | Outstanding |
| 11 | Burnside College Period 202122 | 42.8 | State · Day · 6th | Wallsend, North East | Good |
| 12 | NCEA Duke's Secondary School Period 202425 | 42.6 | Academy · Day · 6th | Ashington, North East | Requires Improvement |
| 13 | Nunthorpe Academy Period 202324 | 42.5 | Academy · Day · 6th | Middlesbrough, North East | Requires Improvement |
| 14 | Ashington Academy Period 202122 | 42.4 | Academy · Day · 6th | Ashington, North East | Good |
| 15 | Southmoor Academy Period 202122 | 42.3 | Academy · Day · 6th | Sunderland, North East | — |
| 16 | St Leonard's Catholic School, Durham Period 202122 | 41.7 | Academy · Day · 6th | Durham, North East | — |
| 17 | Whickham School Period 202122 | 41.5 | Academy · Day · 6th | Newcastle-upon-Tyne, North East | — |
| 18 | St Anthony's Girls' Catholic Academy Period 202324 | 41.5 | Academy · Day · 6th | Sunderland, North East | Good |
| 19 | George Stephenson High School Period 202122 | 41.4 | State · Day · 6th | Newcastle-upon-Tyne, North East | Good |
| 20 | St Mary's Catholic School Period 202223 | 41.4 | Academy · Day · 6th | Newcastle-upon-Tyne, North East | Outstanding |
| 21 | King James I Academy Bishop Auckland Period 202122 | 41.4 | Academy · Day · 6th | Bishop Auckland, North East | — |
| 22 | English Martyrs Catholic School and Sixth Form College Period 202223 | 41.3 | Academy · Day · 6th | Hartlepool, North East | — |
| 23 | Macmillan Academy Period 202223 | 41.3 | Academy · Day · 6th | Middlesbrough, North East | Good |
| 24 | Carmel College Period 202122 | 41.3 | Academy · Day · 6th | Darlington, North East | — |
| 25 | St Aidan's Catholic Academy Period 202122 | 41.1 | Academy · Day · 6th | Sunderland, North East | — |