| 1 | Pate's Grammar School Period 202425 | 71.3% | Grammar · Day · 6th | Cheltenham, South West | Outstanding |
| 2 | Colyton Grammar School Period 202425 | 58.2% | Grammar · Day · 6th | Colyton, South West | Outstanding |
| 3 | Holmleigh Park High School Period 202425 | 43.8% | Academy · Day · 6th | Gloucester, South West | Good |
| 4 | Camborne Science and International Academy Period 202425 | 41.4% | Academy · Day · 6th | Camborne, South West | Good |
| 5 | Launceston College Period 202425 | 34.4% | Academy · Day · 6th | Launceston, South West | Good |
| 6 | Stroud High School Period 202425 | 33.3% | Grammar · Day · 6th | Stroud, South West | Outstanding |
| 7 | Wyedean School and Sixth Form Centre Period 202425 | 33.3% | Academy · Day · 6th | Chepstow, South West | — |
| 8 | Bishop Wordsworth's Church of England Grammar School Period 202425 | 32.8% | Grammar · Day · 6th | Salisbury, South West | Outstanding |
| 9 | Sir Thomas Rich's School Period 202425 | 32.5% | Grammar · Day · 6th | Gloucester, South West | Good |
| 10 | Poole Grammar School Period 202425 | 32.1% | Grammar · Day · 6th | Poole, South West | — |
| 11 | Bristol Free School Period 202425 | 29.5% | Free School · Day · 6th | Bristol, South West | Good |
| 12 | Newquay Tretherras Period 202425 | 28.9% | Academy · Day · 6th | Newquay, South West | — |
| 13 | Matravers School Period 202425 | 28.6% | State · Day · 6th | Westbury, South West | Good |
| 14 | Teignmouth Community School, Exeter Road Period 202425 | 28.6% | Academy · Day · 6th | Teignmouth, South West | — |
| 15 | Bournemouth School Period 202425 | 28.3% | Grammar · Day · 6th | Bournemouth, South West | Outstanding |
| 16 | Torquay Boys' Grammar School Period 202425 | 28.3% | Grammar · Day · 6th | Torquay, South West | Good |
| 17 | The Ridgeway School & Sixth Form College Period 202425 | 28.2% | Academy · Day · 6th | Swindon, South West | Good |
| 18 | The Ilfracombe Church of England Academy Period 202425 | 28.0% | Academy · Day · 6th | Ilfracombe, South West | Requires Improvement |
| 19 | Redland Green School Period 202425 | 28.0% | Academy · Day · 6th | Bristol, South West | Good |
| 20 | Parkstone Grammar School Period 202425 | 26.4% | Grammar · Day · 6th | Poole, South West | — |
| 21 | Chew Valley School Period 202425 | 26.1% | Academy · Day · 6th | Bristol, South West | — |
| 22 | Clyst Vale Community College Period 202425 | 25.0% | Academy · Day · 6th | Exeter, South West | Good |
| 23 | Coombe Dean School Period 202425 | 25.0% | Academy · Day · 6th | Plymouth, South West | Good |
| 24 | Devonport High School for Boys Period 202425 | 25.0% | Grammar · Day · 6th | Plymouth, South West | Good |
| 25 | Marine Academy Plymouth Period 202425 | 25.0% | Academy · Day · 6th | Plymouth, South West | Good |