| 351 | King's Leadership Academy Warrington | 808 pupils | Free School · Day | Warrington, North West | — |
| 352 | The Catholic High School, Chester | 808 pupils | Academy · Day · 6th | Chester, North West | — |
| 353 | Corpus Christi Catholic High School | 807 pupils | State · Day | Preston, North West | — |
| 354 | Harrytown Catholic High School | 803 pupils | State · Day | Stockport, North West | — |
| 355 | The Hollins | 794 pupils | Academy · Day | Accrington, North West | — |
| 356 | St Thomas More RC College | 792 pupils | State · Day | Manchester, North West | — |
| 357 | Queen's Park High School | 785 pupils | Academy · Day · 6th | Chester, North West | — |
| 358 | Longdendale High School | 784 pupils | Academy · Day | Hyde, North West | — |
| 359 | Cardinal Allen Catholic High School, Fleetwood | 783 pupils | State · Day | Fleetwood, North West | — |
| 360 | North Cestrian School | 777 pupils | Free School · Day | Altrincham, North West | — |
| 361 | Lostock Hall Academy | 773 pupils | Academy · Day | Preston, North West | — |
| 362 | Holy Family Roman Catholic and Church of England College | 763 pupils | State · Day | Heywood, North West | — |
| 363 | Brownedge St Mary's Catholic High School | 760 pupils | State · Day | Preston, North West | — |
| 364 | All Hallows RC High School | 737 pupils | State · Day | Salford, North West | — |
| 365 | The Brian Clarke Church of England Academy | 719 pupils | Free School · Day | Oldham, North West | — |
| 366 | Ruskin Community High School | 715 pupils | State · Day | Crewe, North West | — |
| 367 | St Bede's Catholic High School | 706 pupils | State · Day | Ormskirk, North West | — |
| 368 | Dean Trust Rose Bridge | 699 pupils | Academy · Day | Wigan, North West | — |
| 369 | Sir William Stanier School | 688 pupils | Academy · Day | Crewe, North West | — |
| 370 | Carnforth High School | 685 pupils | Academy · Day | Carnforth, North West | — |
| 371 | Rhyddings | 683 pupils | Academy · Day | Accrington, North West | — |
| 372 | Tarleton Academy | 675 pupils | Academy · Day | Preston, North West | — |
| 373 | Sacred Heart Catholic Academy | 653 pupils | Academy · Day · 6th | Liverpool, North West | — |
| 374 | Whitworth Community High School | 651 pupils | State · Day | ROCHDALE, North West | — |
| 375 | St Thomas More Catholic High School | 647 pupils | Academy · Day | Crewe, North West | — |