| 301 | St Bede's Roman Catholic High School, Blackburn | 1,043 pupils | State · Day | Blackburn, North West | — |
| 302 | Pendle Vale College | 1,042 pupils | State · Day | Nelson, North West | — |
| 303 | Kirkbie Kendal School | 1,041 pupils | Academy · Day · 6th | Kendal, North West | — |
| 304 | Holy Family Catholic High School | 1,037 pupils | State · Day · 6th | Liverpool, North West | — |
| 305 | St Peter's RC High School | 1,035 pupils | State · Day | Unknown, North West | — |
| 306 | Richard Rose Central Academy | 1,034 pupils | Academy · Day · 6th | Carlisle, North West | — |
| 307 | St George's School A Church of England Academy | 1,032 pupils | Academy · Day | Blackpool, North West | — |
| 308 | Colne Park High School | 1,031 pupils | Academy · Day | Colne, North West | — |
| 309 | The East Manchester Academy | 1,031 pupils | Academy · Day | Manchester, North West | — |
| 310 | The Elton High School | 1,025 pupils | State · Day | Bury, North West | — |
| 311 | The Winsford Academy | 1,023 pupils | Academy · Day | Winsford, North West | — |
| 312 | Oasis Academy MediaCityUK | 1,013 pupils | Academy · Day | Manchester, North West | — |
| 313 | Stockport Academy | 1,011 pupils | Academy · Day | Stockport, North West | — |
| 314 | Dixons Brooklands Academy | 999 pupils | Academy · Day | Manchester, North West | — |
| 315 | E-ACT Royton and Crompton Academy | 997 pupils | Academy · Day | Oldham, North West | — |
| 316 | St John Fisher Catholic High School | 994 pupils | State · Day | Wigan, North West | — |
| 317 | Accrington Academy | 993 pupils | Academy · Day | Accrington, North West | — |
| 318 | St Benedict's Catholic High School | 992 pupils | State · Day · 6th | Whitehaven, North West | — |
| 319 | Blackburn Central High School | 984 pupils | Academy · Day | Blackburn, North West | — |
| 320 | Holy Cross Catholic High School | 977 pupils | State · Day | Chorley, North West | — |
| 321 | The Derby High School | 951 pupils | State · Day | Lancs, North West | — |
| 322 | Stretford Grammar School | 947 pupils | Grammar · Day · 6th | Manchester, North West | — |
| 323 | Waterhead Academy | 947 pupils | Academy · Day | Oldham, North West | — |
| 324 | Droylsden Academy | 936 pupils | Academy · Day | Manchester, North West | — |
| 325 | Outwood Academy Hindley | 921 pupils | Academy · Day | Wigan, North West | — |