| 251 | Humberston Academy | 890 pupils | Academy · Day | Grimsby, Yorkshire and the Humber | — |
| 252 | Sir John Nelthorpe School | 877 pupils | State · Day · 6th | Brigg, Yorkshire and the Humber | — |
| 253 | Cottingham High School | 869 pupils | Academy · Day | Cottingham, Yorkshire and the Humber | — |
| 254 | Oasis Academy Wintringham | 857 pupils | Academy · Day | Grimsby, Yorkshire and the Humber | — |
| 255 | E-Act Parkwood Academy | 856 pupils | Academy · Day | Sheffield, Yorkshire and the Humber | — |
| 256 | Cleethorpes Academy | 843 pupils | Academy · Day | Cleethorpes, Yorkshire and the Humber | — |
| 257 | Dixons Kings Academy | 832 pupils | Free School · Day | Bradford, Yorkshire and the Humber | — |
| 258 | Lightcliffe Academy | 820 pupils | Academy · Day | Halifax, Yorkshire and the Humber | — |
| 259 | The Boulevard Academy | 811 pupils | Free School · Day | Kingston-upon-Hull, Yorkshire and the Humber | — |
| 260 | Rossett School | 795 pupils | Academy · Day · 6th | Harrogate, Yorkshire and the Humber | — |
| 261 | The Snaith School | 788 pupils | Academy · Day | Goole, Yorkshire and the Humber | — |
| 262 | Wetherby High School | 783 pupils | State · Day | Wetherby, Yorkshire and the Humber | — |
| 263 | Oasis Academy Lister Park | 760 pupils | Academy · Day | Bradford, Yorkshire and the Humber | — |
| 264 | Withernsea High School | 731 pupils | State · Day | Withernsea, Yorkshire and the Humber | — |
| 265 | George Pindar School | 727 pupils | Academy · Day | Scarborough, Yorkshire and the Humber | — |
| 266 | The Holy Family Catholic School, a Voluntary Academy | 700 pupils | Academy · Day | Keighley, Yorkshire and the Humber | — |
| 267 | Beckfoot Upper Heaton | 682 pupils | Academy · Day | Bradford, Yorkshire and the Humber | — |
| 268 | The Vale Academy | 680 pupils | Academy · Day · 6th | Brigg, Yorkshire and the Humber | — |
| 269 | Dixons Trinity Academy | 678 pupils | Free School · Day | Bradford, Yorkshire and the Humber | — |
| 270 | Howden School | 678 pupils | Academy · Day | Goole, Yorkshire and the Humber | — |
| 271 | Beacon Academy | 666 pupils | Academy · Day | Cleethorpes, Yorkshire and the Humber | — |
| 272 | St Francis Xavier School - a Joint Catholic and Church of England Voluntary Academy | 606 pupils | Academy · Day | Richmond, Yorkshire and the Humber | — |
| 273 | Settle College | 586 pupils | State · Day · 6th | Settle, Yorkshire and the Humber | — |
| 274 | St Augustine's Catholic School - a Catholic voluntary academy | 583 pupils | Academy · Day | Scarborough, Yorkshire and the Humber | — |
| 275 | Oasis Academy Immingham | 582 pupils | Academy · Day | Immingham, Yorkshire and the Humber | — |