| 251 | John F Kennedy Catholic School | 1,078 pupils | Academy · Day · 6th | Hemel Hempstead, East of England | — |
| 252 | Ormiston Rivers Academy | 1,077 pupils | Academy · Day · 6th | Burnham-on-Crouch, East of England | — |
| 253 | Alec Hunter Academy | 1,067 pupils | Academy · Day | Braintree, East of England | — |
| 254 | Hartismere School | 1,051 pupils | Academy · Day · 6th | Eye, East of England | — |
| 255 | Debden Park High School | 1,050 pupils | Academy · Day · 6th | Loughton, East of England | — |
| 256 | Westbourne Academy | 1,038 pupils | Academy · Day | Ipswich, East of England | — |
| 257 | The Gateway Academy | 1,033 pupils | Academy · Day | Grays, East of England | — |
| 258 | Thurstable School | 1,031 pupils | Academy · Day | Colchester, East of England | — |
| 259 | Freman College | 1,022 pupils | Academy · Day · 6th | Buntingford, East of England | — |
| 260 | Future Academies Watford | 1,018 pupils | Academy · Day · 6th | Watford, East of England | — |
| 261 | Reepham High School and College | 1,015 pupils | Academy · Day · 6th | Norwich, East of England | — |
| 262 | Bungay High School | 996 pupils | Academy · Day · 6th | Bungay, East of England | — |
| 263 | Stratton School | 986 pupils | Academy · Day · 6th | Biggleswade, East of England | — |
| 264 | The Thomas Alleyne Academy | 986 pupils | Academy · Day · 6th | Stevenage, East of England | — |
| 265 | St Benedict's Catholic School | 976 pupils | Academy · Day · 6th | Bury St Edmunds, East of England | — |
| 266 | The Grange Academy | 934 pupils | Academy · Day · 6th | Bushey, East of England | — |
| 267 | Lincroft Academy | 931 pupils | Academy · Day | Bedford, East of England | — |
| 268 | Ridgeway Academy | 929 pupils | Academy · Day · 6th | Welwyn Garden City, East of England | — |
| 269 | The Thomas Lord Audley School | 921 pupils | Academy · Day | Colchester, East of England | — |
| 270 | Attleborough Academy | 920 pupils | Academy · Day · 6th | Attleborough, East of England | — |
| 271 | Diss High School | 918 pupils | Academy · Day · 6th | Diss, East of England | — |
| 272 | Manningtree High School | 917 pupils | Academy · Day | Manningtree, East of England | — |
| 273 | Ormiston Venture Academy | 902 pupils | Academy · Day | Gorleston, East of England | — |
| 274 | Stowmarket High School | 896 pupils | Academy · Day · 6th | Stowmarket, East of England | — |
| 275 | Great Yarmouth Charter Academy | 895 pupils | Free School · Day | Great Yarmouth, East of England | — |