| 1 | Dame Alice Owen's School Period 202425 | 72.9 | Academy · Day · 6th | Potters Bar, East of England | Outstanding |
| 2 | Chesterton Community College Period 202425 | 68.0 | Academy · Day · 6th | Cambridge, East of England | — |
| 3 | Parmiter's School Period 202425 | 66.5 | Academy · Day · 6th | Watford, East of England | Outstanding |
| 4 | Sandringham School Period 202425 | 65.1 | Academy · Day · 6th | St Albans, East of England | Outstanding |
| 5 | St Clement Danes School Period 202425 | 65.1 | Academy · Day · 6th | Rickmansworth, East of England | Outstanding |
| 6 | St George's School Period 202425 | 63.7 | Academy · Boarding · 6th | Harpenden, East of England | — |
| 7 | Parkside Community College Period 202425 | 63.5 | Academy · Day | Cambridge, East of England | — |
| 8 | Sir John Lawes School Period 202425 | 62.8 | Academy · Day · 6th | Harpenden, East of England | Outstanding |
| 9 | Beaumont School Period 202425 | 62.6 | Academy · Day · 6th | St Albans, East of England | — |
| 10 | Hockerill Anglo-European College Period 202425 | 61.7 | Academy · Boarding · 6th | Bishop's Stortford, East of England | Good |
| 11 | Yavneh College Period 202425 | 61.6 | Academy · Day · 6th | Borehamwood, East of England | Good |
| 12 | St Bede's Inter-Church School Period 202425 | 61.6 | Academy · Day | Cambridge, East of England | Outstanding |
| 13 | Notre Dame High School, Norwich Period 202425 | 61.3 | Academy · Day · 6th | Norwich, East of England | Good |
| 14 | Rickmansworth School Period 202425 | 61.2 | Academy · Day · 6th | Rickmansworth, East of England | Outstanding |
| 15 | Saffron Walden County High School Period 202425 | 59.7 | Academy · Day · 6th | Saffron Walden, East of England | Outstanding |
| 16 | Roundwood Park School Period 202425 | 59.5 | Academy · Day · 6th | Harpenden, East of England | Outstanding |
| 17 | Hethersett Academy Period 202425 | 59.0 | Academy · Day | Norwich, East of England | — |
| 18 | Impington Village College Period 202425 | 58.6 | Academy · Day · 6th | Cambridge, East of England | — |
| 19 | Moulsham High School Period 202425 | 58.3 | Academy · Day · 6th | Chelmsford, East of England | Good |
| 20 | Ashlyns School Period 202425 | 57.9 | State · Day · 6th | Berkhamsted, East of England | Good |
| 21 | The Saint John Henry Newman Catholic School Period 202425 | 57.9 | Academy · Day · 6th | Stevenage, East of England | — |
| 22 | Queens' School Period 202425 | 57.5 | Academy · Day · 6th | Bushey, East of England | — |
| 23 | Cambridge Academy for Science and Technology Period 202425 | 56.8 | Free School · Day · 6th | Cambridge, East of England | — |
| 24 | Davenant Foundation School Period 202425 | 56.7 | Academy · Day · 6th | Loughton, East of England | Good |
| 25 | Nicholas Breakspear Catholic School Period 202425 | 56.4 | Academy · Day · 6th | St Albans, East of England | Outstanding |