| 1 | South Wilts Grammar School Period 202425 | 98.7% | Grammar · Day · 6th | Salisbury, South West | Good |
| 2 | Devonport High School for Girls Period 202425 | 97.6% | Grammar · Day · 6th | Plymouth, South West | Good |
| 3 | Stroud High School Period 202425 | 97.5% | Grammar · Day · 6th | Stroud, South West | Outstanding |
| 4 | Bournemouth School for Girls Period 202425 | 96.0% | Grammar · Day · 6th | Bournemouth, South West | Outstanding |
| 5 | Denmark Road High School Period 202425 | 94.2% | Grammar · Day · 6th | Gloucester, South West | Good |
| 6 | Ribston Hall High School Period 202425 | 90.5% | Grammar · Day · 6th | Gloucester, South West | — |
| 7 | Plymouth High School for Girls Period 202425 | 90.3% | Grammar · Day · 6th | Plymouth, South West | — |
| 8 | Parkstone Grammar School Period 202425 | 90.3% | Grammar · Day · 6th | Poole, South West | — |
| 9 | Torquay Girls' Grammar School Period 202425 | 89.7% | Grammar · Day · 6th | Torquay, South West | Outstanding |
| 10 | Glenmoor Academy Period 202425 | 78.6% | Academy · Day | Bournemouth, South West | — |
| 11 | Avonbourne Girls Academy Period 202425 | 61.7% | Academy · Day · 6th | Bournemouth, South West | — |
| 12 | E-Act Montpelier High School Period 202425 | 61.1% | Academy · Day · 6th | Bristol, South West | Inadequate |
| 13 | Hayesfield Girls School Period 202425 | 60.0% | Academy · Day · 6th | Bath, South West | — |
| 14 | Notre Dame RC School Period 202425 | 33.6% | Academy · Day · 6th | Plymouth, South West | — |