| 1 | Altrincham Grammar School for Girls Period 202425 | 8.01 | Grammar · Day · 6th | Altrincham, North West | Outstanding |
| 2 | Lancaster Girls' Grammar School Period 202425 | 7.06 | Grammar · Day · 6th | Lancaster, North West | Good |
| 3 | Tauheedul Islam Girls' High School Period 202425 | 6.97 | Academy · Day · 6th | Blackburn, North West | Outstanding |
| 4 | Loreto Grammar School Period 202425 | 6.90 | Grammar · Day · 6th | Altrincham, North West | Outstanding |
| 5 | West Kirby Grammar School Period 202425 | 6.80 | Grammar · Day · 6th | Wirral, North West | Good |
| 6 | Wirral Grammar School for Girls Period 202425 | 6.44 | Grammar · Day · 6th | Wirral, North West | Outstanding |
| 7 | Upton Hall School FCJ Period 202425 | 6.29 | Grammar · Day · 6th | Wirral, North West | Outstanding |
| 8 | Eden Girls' Leadership Academy, Manchester Period 202425 | 5.55 | Free School · Day | Manchester, North West | Good |
| 9 | Preston Muslim Girls High School Period 202425 | 5.32 | State · Day | Preston, North West | — |
| 10 | Bolton Muslim Girls School Period 202425 | 5.13 | Academy · Day | Bolton, North West | — |
| 11 | Levenshulme High School Period 202425 | 5.08 | Academy · Day | Manchester, North West | — |
| 12 | Sandbach High School and Sixth Form College Period 202425 | 5.06 | Academy · Day · 6th | Sandbach, North West | Good |
| 13 | Penwortham Girls' High School Period 202425 | 5.05 | State · Day | Preston, North West | Outstanding |
| 14 | Whalley Range 11-18 High School Period 202425 | 4.91 | Academy · Day · 6th | Manchester, North West | — |
| 15 | Archbishop Blanch CofE High School Period 202425 | 4.89 | Academy · Day · 6th | Liverpool, North West | Outstanding |
| 16 | Fairfield High School for Girls Period 202425 | 4.84 | Academy · Day | Manchester, North West | Good |
| 17 | The Belvedere Academy Period 202425 | 4.78 | Academy · Day · 6th | Liverpool, North West | — |
| 18 | Greenbank High School Period 202425 | 4.69 | Academy · Day | Southport, North West | Good |
| 19 | Beis Yaakov High School Period 202425 | 4.43 | Academy · Day | Salford, North West | — |
| 20 | Holly Lodge Girls' College Period 202425 | 4.32 | State · Day · 6th | Liverpool, North West | — |
| 21 | Flixton Girls School Period 202425 | 4.25 | Academy · Day | Manchester, North West | Good |
| 22 | Bellerive FCJ Catholic College Period 202425 | 3.97 | Academy · Day · 6th | Liverpool, North West | — |
| 23 | St Julie's Catholic High School Period 202425 | 3.75 | State · Day · 6th | Liverpool, North West | — |
| 24 | Weatherhead High School Period 202425 | 3.71 | Academy · Day · 6th | Wallasey, North West | Good |
| 25 | St John Bosco Arts College Period 202425 | 3.55 | State · Day · 6th | Croxteth, North West | Good |