| 1 | South Wilts Grammar School Period 202425 | 77.0 | Grammar · Day · 6th | Salisbury, South West | Good |
| 2 | Stroud High School Period 202425 | 76.9 | Grammar · Day · 6th | Stroud, South West | Outstanding |
| 3 | Devonport High School for Girls Period 202425 | 73.8 | Grammar · Day · 6th | Plymouth, South West | Good |
| 4 | Denmark Road High School Period 202425 | 72.9 | Grammar · Day · 6th | Gloucester, South West | Good |
| 5 | Bournemouth School for Girls Period 202425 | 72.2 | Grammar · Day · 6th | Bournemouth, South West | Outstanding |
| 6 | Torquay Girls' Grammar School Period 202425 | 68.6 | Grammar · Day · 6th | Torquay, South West | Outstanding |
| 7 | Parkstone Grammar School Period 202425 | 68.5 | Grammar · Day · 6th | Poole, South West | — |
| 8 | Ribston Hall High School Period 202425 | 67.7 | Grammar · Day · 6th | Gloucester, South West | — |
| 9 | Plymouth High School for Girls Period 202425 | 65.5 | Grammar · Day · 6th | Plymouth, South West | — |
| 10 | Glenmoor Academy Period 202425 | 60.7 | Academy · Day | Bournemouth, South West | — |
| 11 | E-Act Montpelier High School Period 202425 | 57.3 | Academy · Day · 6th | Bristol, South West | Inadequate |
| 12 | Hayesfield Girls School Period 202425 | 57.0 | Academy · Day · 6th | Bath, South West | — |
| 13 | Avonbourne Girls Academy Period 202425 | 53.0 | Academy · Day · 6th | Bournemouth, South West | — |
| 14 | Notre Dame RC School Period 202425 | 43.3 | Academy · Day · 6th | Plymouth, South West | — |