| 1 | Sir Thomas Rich's School Period 202425 | 77.2 | Grammar · Day · 6th | Gloucester, South West | Good |
| 2 | Bournemouth School Period 202425 | 74.2 | Grammar · Day · 6th | Bournemouth, South West | Outstanding |
| 3 | Marling School Period 202425 | 73.9 | Grammar · Day · 6th | Stroud, South West | — |
| 4 | Bishop Wordsworth's Church of England Grammar School Period 202425 | 73.1 | Grammar · Day · 6th | Salisbury, South West | Outstanding |
| 5 | Torquay Boys' Grammar School Period 202425 | 70.8 | Grammar · Day · 6th | Torquay, South West | Good |
| 6 | Poole Grammar School Period 202425 | 70.2 | Grammar · Day · 6th | Poole, South West | — |
| 7 | Devonport High School for Boys Period 202425 | 69.3 | Grammar · Day · 6th | Plymouth, South West | Good |
| 8 | Winton Academy Period 202425 | 55.4 | Academy · Day | Bournemouth, South West | — |
| 9 | Beechen Cliff School Period 202425 | 55.0 | Academy · Boarding · 6th | Bath, South West | Good |
| 10 | Avonbourne Boys' Academy Period 202425 | 47.3 | Academy · Day | Bournemouth, South West | Outstanding |
| 11 | Brymore Academy Period 202425 | 44.0 | Academy · Boarding | Bridgwater, South West | — |
| 12 | SGS Berkeley Green UTC Period 202425 | 41.2 | Free School · Day · 6th | Berkeley, South West | Good |
| 13 | St Boniface's RC College Period 202425 | 39.0 | Academy · Day · 6th | Plymouth, South West | — |
| 14 | UTC Swindon Period 202425 | 32.4 | Free School · Day · 6th | Swindon, South West | Requires Improvement |