| 26 | Poole Grammar School Period 202425 | 46.9 | Grammar · Day · 6th | Poole, South West | — |
| 27 | Westcliff High School for Boys Academy Period 202122 | 46.9 | Grammar · Day · 6th | Westcliff-on-Sea, East of England | Outstanding |
| 28 | Sir Thomas Rich's School Period 202122 | 46.8 | Grammar · Day · 6th | Gloucester, South West | Good |
| 29 | Lawrence Sheriff School Period 202122 | 46.6 | Grammar · Day · 6th | Rugby, West Midlands | Outstanding |
| 30 | Dartford Grammar School Period 202122 | 46.4 | Grammar · Day · 6th | Dartford, South East | Outstanding |
| 31 | The Cardinal Vaughan Memorial RC School Period 202122 | 46.4 | Academy · Day · 6th | London, London | Outstanding |
| 32 | Aylesbury Grammar School Period 202122 | 46.2 | Grammar · Day · 6th | Aylesbury, South East | Outstanding |
| 33 | The King's School, Grantham Period 202122 | 46.1 | Grammar · Day · 6th | Grantham, East Midlands | Good |
| 34 | Saint Ambrose College Period 202324 | 46.1 | Grammar · Day · 6th | Altrincham, North West | Good |
| 35 | Bishop Wordsworth's Church of England Grammar School Period 202122 | 46.1 | Grammar · Day · 6th | Salisbury, South West | Outstanding |
| 36 | Hasmonean High School for Boys Period 202122 | 45.7 | Academy · Day · 6th | London, London | Good |
| 37 | Sir Joseph Williamson's Mathematical School Period 202122 | 45.7 | Grammar · Day · 6th | Rochester, South East | Outstanding |
| 38 | John Hampden Grammar School Period 202425 | 45.5 | Grammar · Day · 6th | High Wycombe, South East | Outstanding |
| 39 | SGS Berkeley Green UTC Period 202122 | 45.0 | Free School · Day · 6th | Berkeley, South West | Good |
| 40 | Lancaster Royal Grammar School Period 202122 | 44.6 | Grammar · Boarding · 6th | Lancaster, North West | Good |
| 41 | Hutton Church of England Grammar School Period 202122 | 44.4 | State · Day · 6th | Preston, North West | — |
| 42 | Ilford County High School Period 202122 | 44.3 | Grammar · Day · 6th | Ilford, London | Good |
| 43 | University Technical College Leeds Period 202122 | 44.3 | Free School · Day · 6th | Leeds, Yorkshire and the Humber | Good |
| 44 | Carre's Grammar School Period 202122 | 44.2 | Grammar · Day · 6th | Sleaford, East Midlands | Good |
| 45 | Torquay Boys' Grammar School Period 202122 | 43.9 | Grammar · Day · 6th | Torquay, South West | Good |
| 46 | Harris Boys' Academy East Dulwich Period 202425 | 43.9 | Academy · Day · 6th | London, London | Outstanding |
| 47 | Watford Grammar School for Boys Period 202122 | 43.6 | Academy · Day · 6th | Watford, East of England | Outstanding |
| 48 | St Bonaventure's RC School Period 202122 | 43.5 | State · Day · 6th | London, London | Outstanding |
| 49 | Mulberry Stepney Green Mathematics and Computing College Period 202122 | 43.5 | Academy · Day · 6th | London, London | — |
| 50 | Haberdashers' Adams Period 202122 | 43.5 | Grammar · Boarding · 6th | Newport, West Midlands | Good |