| 1726 | Cheadle Hulme High School | 1,690 pupils | Academy · Day · 6th | Cheadle, North West | — |
| 1727 | Durham Johnston Comprehensive School | 1,688 pupils | State · Day · 6th | Durham, North East | — |
| 1728 | Royal Wootton Bassett Academy | 1,688 pupils | Academy · Day · 6th | Swindon, South West | — |
| 1729 | Ormiston Forge Academy | 1,686 pupils | Academy · Day · 6th | Cradley Heath, West Midlands | — |
| 1730 | Queen Katharine Academy | 1,685 pupils | Academy · Day · 6th | Peterborough, East of England | — |
| 1731 | Sharnbrook Academy | 1,685 pupils | Academy · Day · 6th | Bedford, East of England | — |
| 1732 | Little Heath School | 1,679 pupils | State · Day · 6th | Reading, South East | — |
| 1733 | Rainford High School | 1,675 pupils | Academy · Day · 6th | St Helens, North West | — |
| 1734 | Trinity School | 1,675 pupils | Academy · Day · 6th | Carlisle, North West | — |
| 1735 | Kettlethorpe High School | 1,672 pupils | State · Day | Wakefield, Yorkshire and the Humber | — |
| 1736 | High Storrs School | 1,668 pupils | Academy · Day · 6th | Sheffield, Yorkshire and the Humber | — |
| 1737 | Alderbrook School | 1,667 pupils | Academy · Day · 6th | Solihull, West Midlands | — |
| 1738 | The Regis School | 1,665 pupils | Academy · Day · 6th | West Sussex, South East | — |
| 1739 | Queens' School | 1,660 pupils | Academy · Day · 6th | Bushey, East of England | — |
| 1740 | Samuel Whitbread Academy | 1,660 pupils | Academy · Day · 6th | Shefford, East of England | — |
| 1741 | Oasis Academy Shirley Park | 1,659 pupils | Academy · Day · 6th | Croydon, London | — |
| 1742 | Claremont High School | 1,657 pupils | Academy · Day · 6th | Harrow, London | — |
| 1743 | Cotham School | 1,655 pupils | Academy · Day · 6th | Bristol, South West | — |
| 1744 | Rodillian Academy | 1,654 pupils | Academy · Day · 6th | Wakefield, Yorkshire and the Humber | — |
| 1745 | Newquay Tretherras | 1,653 pupils | Academy · Day · 6th | Newquay, South West | — |
| 1746 | Arthur Mellows Village College | 1,651 pupils | Academy · Day · 6th | Peterborough, East of England | — |
| 1747 | Beaumont School | 1,651 pupils | Academy · Day · 6th | St Albans, East of England | — |
| 1748 | Mill Hill County High School | 1,651 pupils | Academy · Day · 6th | London, London | — |
| 1749 | Highlands School | 1,650 pupils | State · Day · 6th | London, London | — |
| 1750 | Ely College | 1,649 pupils | Academy · Day · 6th | Ely, East of England | — |