| 326 | Shuttleworth College | 1,079 pupils | State · Day | Burnley, North West | — |
| 327 | Eaton Bank Academy | 1,077 pupils | Academy · Day · 6th | Congleton, North West | — |
| 328 | St Monica's RC High School, a Voluntary Academy | 1,066 pupils | Academy · Day | Manchester, North West | — |
| 329 | Darwen Aldridge Community Academy | 1,065 pupils | Academy · Day · 6th | Darwen, North West | — |
| 330 | St Joseph's RC High School | 1,051 pupils | State · Day | Bolton, North West | — |
| 331 | The Hathershaw College | 1,051 pupils | Academy · Day | Oldham, North West | — |
| 332 | Our Lady's RC High School | 1,050 pupils | State · Day | Manchester, North West | — |
| 333 | Levenshulme High School | 1,048 pupils | Academy · Day | Manchester, North West | — |
| 334 | The County High School, Leftwich | 1,048 pupils | Academy · Day | Northwich, North West | — |
| 335 | St Bede's Roman Catholic High School, Blackburn | 1,043 pupils | State · Day | Blackburn, North West | — |
| 336 | Pendle Vale College | 1,042 pupils | State · Day | Nelson, North West | — |
| 337 | Kirkbie Kendal School | 1,041 pupils | Academy · Day · 6th | Kendal, North West | — |
| 338 | Holy Family Catholic High School | 1,037 pupils | State · Day · 6th | Liverpool, North West | — |
| 339 | St Peter's RC High School | 1,035 pupils | State · Day | Unknown, North West | — |
| 340 | Richard Rose Central Academy | 1,034 pupils | Academy · Day · 6th | Carlisle, North West | — |
| 341 | St George's School A Church of England Academy | 1,032 pupils | Academy · Day | Blackpool, North West | — |
| 342 | Colne Park High School | 1,031 pupils | Academy · Day | Colne, North West | — |
| 343 | The East Manchester Academy | 1,031 pupils | Academy · Day | Manchester, North West | — |
| 344 | The Elton High School | 1,025 pupils | State · Day | Bury, North West | — |
| 345 | The Winsford Academy | 1,023 pupils | Academy · Day | Winsford, North West | — |
| 346 | Oasis Academy MediaCityUK | 1,013 pupils | Academy · Day | Manchester, North West | — |
| 347 | Stockport Academy | 1,011 pupils | Academy · Day | Stockport, North West | — |
| 348 | St Julie's Catholic High School | 1,009 pupils | State · Day · 6th | Liverpool, North West | — |
| 349 | Holly Lodge Girls' College | 1,000 pupils | State · Day · 6th | Liverpool, North West | — |
| 350 | Dixons Brooklands Academy | 999 pupils | Academy · Day | Manchester, North West | — |