| 251 | Tudor Grange Academy Kingshurst | 1,189 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 252 | The Coleshill School | 1,188 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 253 | Heath Park | 1,187 pupils | Academy · Day · 6th | Wolverhampton, West Midlands | — |
| 254 | West Walsall E-ACT Academy | 1,186 pupils | Academy · Day · 6th | Walsall, West Midlands | — |
| 255 | St Michael's Church of England High School | 1,178 pupils | State · Day | Rowley Regis, West Midlands | — |
| 256 | The University of Birmingham School | 1,177 pupils | Free School · Day · 6th | Birmingham, West Midlands | — |
| 257 | Etone College | 1,170 pupils | Academy · Day · 6th | Nuneaton, West Midlands | — |
| 258 | Idsall School | 1,170 pupils | Academy · Day · 6th | Shifnal, West Midlands | — |
| 259 | Ernesford Grange Community Academy | 1,163 pupils | Academy · Day · 6th | Coventry, West Midlands | — |
| 260 | Q3 Academy Great Barr | 1,163 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 261 | Ormiston Sandwell Community Academy | 1,159 pupils | Academy · Day | Oldbury, West Midlands | — |
| 262 | Archbishop Ilsley Catholic School | 1,158 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 263 | Lode Heath School | 1,155 pupils | Academy · Day | Solihull, West Midlands | — |
| 264 | St Edmund Campion Catholic School | 1,151 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 265 | St Margaret Ward Catholic Academy | 1,139 pupils | Academy · Day · 6th | Stoke-on-Trent, West Midlands | — |
| 266 | St Joseph's College | 1,132 pupils | Grammar · Day · 6th | Stoke-on-Trent, West Midlands | — |
| 267 | Colton Hills Community School | 1,131 pupils | State · Day · 6th | Wolverhampton, West Midlands | — |
| 268 | Erasmus Darwin Academy | 1,128 pupils | Academy · Day · 6th | Burntwood, West Midlands | — |
| 269 | St Edmund's Catholic Academy | 1,128 pupils | Academy · Day · 6th | Wolverhampton, West Midlands | — |
| 270 | St Thomas More Catholic Academy | 1,119 pupils | Academy · Day · 6th | Stoke-on-Trent, West Midlands | — |
| 271 | St Francis of Assisi Catholic College | 1,113 pupils | State · Day · 6th | Walsall, West Midlands | — |
| 272 | E-ACT North Birmingham Academy | 1,112 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 273 | Cannock Chase High School | 1,109 pupils | Academy · Day · 6th | Cannock, West Midlands | — |
| 274 | Thistley Hough Academy | 1,095 pupils | Academy · Day | Stoke-on-Trent, West Midlands | — |
| 275 | St Thomas More Catholic School and Sixth Form College | 1,093 pupils | Academy · Day · 6th | Nuneaton, West Midlands | — |