| 226 | Moseley School and Sixth Form | 1,428 pupils | State · Day · 6th | Birmingham, West Midlands | — |
| 227 | Saltley Academy | 1,380 pupils | Academy · Day | Birmingham, West Midlands | — |
| 228 | King Edward VI Handsworth School | 1,324 pupils | Grammar · Day · 6th | Birmingham, West Midlands | — |
| 229 | St Peter's Catholic School | 1,311 pupils | Academy · Day · 6th | Solihull, West Midlands | — |
| 230 | St Peter's Collegiate Academy | 1,306 pupils | Academy · Day · 6th | Wolverhampton, West Midlands | — |
| 231 | John Henry Newman Catholic College | 1,301 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 232 | Shire Oak Academy | 1,297 pupils | Academy · Day · 6th | Walsall, West Midlands | — |
| 233 | Aldersley High School | 1,293 pupils | Academy · Day · 6th | Wolverhampton, West Midlands | — |
| 234 | John Kyrle High School and Sixth Form Centre Academy | 1,292 pupils | Academy · Day · 6th | Ross-on-Wye, West Midlands | — |
| 235 | Park Hall Academy | 1,270 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |
| 236 | Walton High School | 1,270 pupils | Academy · Day · 6th | Stafford, West Midlands | — |
| 237 | Co-op Academy Stoke-On-Trent | 1,248 pupils | Academy · Day | Stoke-on-Trent, West Midlands | — |
| 238 | Hadley Learning Community - Secondary Phase | 1,248 pupils | Academy · Day | Telford, West Midlands | — |
| 239 | Bishop Challoner Catholic College | 1,246 pupils | State · Day · 6th | Birmingham, West Midlands | — |
| 240 | Campion School | 1,236 pupils | Academy · Day · 6th | Leamington Spa, West Midlands | — |
| 241 | Chase Terrace Academy | 1,230 pupils | Academy · Day · 6th | Burntwood, West Midlands | — |
| 242 | The Friary School | 1,220 pupils | Academy · Day · 6th | Lichfield, West Midlands | — |
| 243 | Heart of England School | 1,216 pupils | Academy · Day · 6th | Coventry, West Midlands | — |
| 244 | The Hart School | 1,216 pupils | Academy · Day · 6th | Rugeley, West Midlands | — |
| 245 | Gospel Oak School | 1,210 pupils | Academy · Day · 6th | Tipton, West Midlands | — |
| 246 | The Excel Academy | 1,208 pupils | Academy · Day | Stoke-on-Trent, West Midlands | — |
| 247 | Hodge Hill College | 1,205 pupils | State · Day | Birmingham, West Midlands | — |
| 248 | Our Lady and St Chad Catholic Academy | 1,191 pupils | Academy · Day · 6th | Wolverhampton, West Midlands | — |
| 249 | Ormiston Sir Stanley Matthews Academy | 1,190 pupils | Academy · Day | Stoke-on-Trent, West Midlands | — |
| 250 | St Thomas Aquinas Catholic School | 1,190 pupils | Academy · Day · 6th | Birmingham, West Midlands | — |