| 1551 | Chesterfield High School | 1,628 pupils | Academy · Day · 6th | Liverpool, North West | — |
| 1552 | King Edward VI School | 1,627 pupils | State · Day · 6th | Lichfield, West Midlands | — |
| 1553 | Ringwood School Academy | 1,626 pupils | Academy · Day · 6th | Ringwood, South East | — |
| 1554 | Park View School | 1,617 pupils | Academy · Day · 6th | Chester le Street, North East | — |
| 1555 | Abbey Grange Church of England Academy | 1,615 pupils | Academy · Day · 6th | Leeds, Yorkshire and the Humber | — |
| 1556 | Thomas Gainsborough School | 1,615 pupils | Academy · Day · 6th | Sudbury, East of England | — |
| 1557 | Blessed Thomas Holford Catholic College | 1,614 pupils | State · Day · 6th | Altrincham, North West | — |
| 1558 | Ryburn Valley High School | 1,614 pupils | Academy · Day · 6th | Sowerby Bridge, Yorkshire and the Humber | — |
| 1559 | The Chalk Hills Academy | 1,614 pupils | Academy · Day · 6th | Luton, East of England | — |
| 1560 | Lift Greensward | 1,613 pupils | Academy · Day · 6th | Hockley, East of England | — |
| 1561 | Co-op Academy Manchester | 1,610 pupils | Academy · Day | Manchester, North West | — |
| 1562 | Goffs Academy | 1,606 pupils | Academy · Day · 6th | Waltham Cross, East of England | — |
| 1563 | Beckfoot School | 1,605 pupils | Academy · Day · 6th | Bingley, Yorkshire and the Humber | — |
| 1564 | The Saint John Henry Newman Catholic School | 1,605 pupils | Academy · Day · 6th | Stevenage, East of England | — |
| 1565 | Ashton-on-Mersey School | 1,600 pupils | Academy · Day · 6th | Sale, North West | — |
| 1566 | Oakwood School | 1,600 pupils | State · Day | Horley, South East | — |
| 1567 | Sackville School | 1,599 pupils | State · Day · 6th | East Grinstead, South East | — |
| 1568 | Christopher Whitehead Language College | 1,596 pupils | Academy · Day · 6th | Worcester, West Midlands | — |
| 1569 | Valley Park School | 1,595 pupils | Academy · Day · 6th | Maidstone, South East | — |
| 1570 | Lytchett Minster School | 1,590 pupils | State · Day · 6th | Poole, South West | — |
| 1571 | The Hazeley Academy | 1,590 pupils | Academy · Day · 6th | Milton Keynes, South East | — |
| 1572 | Brentside High School | 1,589 pupils | State · Day · 6th | London, London | — |
| 1573 | St Robert of Newminster Catholic School and Sixth Form College, Washington | 1,588 pupils | Academy · Day · 6th | Washington, North East | — |
| 1574 | Aldridge School - A Science College | 1,585 pupils | Academy · Day · 6th | Walsall, West Midlands | — |
| 1575 | Tring School | 1,584 pupils | Academy · Day · 6th | Tring, East of England | — |