| 1501 | Whitmore High School | 1,739 pupils | State · Day · 6th | Harrow, London | — |
| 1502 | Outwood Academy Portland | 1,726 pupils | Academy · Day · 6th | Worksop, East Midlands | — |
| 1503 | Neston High School | 1,724 pupils | Academy · Day · 6th | Neston, North West | — |
| 1504 | Whickham School | 1,721 pupils | Academy · Day · 6th | Newcastle-upon-Tyne, North East | — |
| 1505 | Collingwood College | 1,714 pupils | Academy · Day · 6th | Camberley, South East | — |
| 1506 | Kenton School | 1,713 pupils | Academy · Day · 6th | Newcastle-upon-Tyne, North East | — |
| 1507 | St John's Marlborough | 1,712 pupils | Academy · Day · 6th | Marlborough, South West | — |
| 1508 | St Martin's School Brentwood | 1,711 pupils | Academy · Day · 6th | Brentwood, East of England | — |
| 1509 | Derby Moor Spencer Academy | 1,709 pupils | Academy · Day · 6th | Derby, East Midlands | — |
| 1510 | Northgate High School | 1,709 pupils | State · Day · 6th | Ipswich, East of England | — |
| 1511 | City of Norwich School, An Ormiston Academy | 1,708 pupils | Academy · Day · 6th | Norwich, East of England | — |
| 1512 | Finham Park School | 1,705 pupils | Academy · Day · 6th | Coventry, West Midlands | — |
| 1513 | Tudor Grange Academy, Solihull | 1,705 pupils | Academy · Day · 6th | Solihull, West Midlands | — |
| 1514 | Cheney School | 1,704 pupils | Academy · Day · 6th | Oxford, South East | — |
| 1515 | The Billericay School | 1,702 pupils | Academy · Day · 6th | Billericay, East of England | — |
| 1516 | Allerton High School | 1,697 pupils | State · Day · 6th | Leeds, Yorkshire and the Humber | — |
| 1517 | Cheadle Hulme High School | 1,690 pupils | Academy · Day · 6th | Cheadle, North West | — |
| 1518 | Durham Johnston Comprehensive School | 1,688 pupils | State · Day · 6th | Durham, North East | — |
| 1519 | Royal Wootton Bassett Academy | 1,688 pupils | Academy · Day · 6th | Swindon, South West | — |
| 1520 | Ormiston Forge Academy | 1,686 pupils | Academy · Day · 6th | Cradley Heath, West Midlands | — |
| 1521 | Queen Katharine Academy | 1,685 pupils | Academy · Day · 6th | Peterborough, East of England | — |
| 1522 | Sharnbrook Academy | 1,685 pupils | Academy · Day · 6th | Bedford, East of England | — |
| 1523 | Little Heath School | 1,679 pupils | State · Day · 6th | Reading, South East | — |
| 1524 | Rainford High School | 1,675 pupils | Academy · Day · 6th | St Helens, North West | — |
| 1525 | Trinity School | 1,675 pupils | Academy · Day · 6th | Carlisle, North West | — |