| 1 | Nottingham High School Period 202122 | 51.4 | Independent · Day · 6th | Nottingham, East Midlands | — |
| 2 | Uppingham School Period 202425 | 50.0 | Independent · Boarding · 6th | Unknown, East Midlands | — |
| 3 | Leicester Grammar School Trust Period 202122 | 49.2 | Independent · Day · 6th | Leicester, East Midlands | — |
| 4 | Leicester High School for Girls Period 202122 | 49.2 | Independent · Day · 6th | Unknown, East Midlands | — |
| 5 | Oundle School Period 202122 | 48.7 | Independent · Boarding · 6th | Northamptonshire, East Midlands | — |
| 6 | Nottingham Girls' High School GDST Period 202122 | 47.9 | Independent · Day · 6th | Unknown, East Midlands | — |
| 7 | Loughborough High School Period 202425 | 47.8 | Independent · Boarding · 6th | Unknown, East Midlands | — |
| 8 | Oneschool Global Uk, Northampton Campus Period 202425 | 46.0 | Independent · Day · 6th | Northampton, East Midlands | — |
| 9 | Ratcliffe College Period 202122 | 45.8 | Independent · Boarding · 6th | Unknown, East Midlands | — |
| 10 | Derby High School Period 202223 | 44.4 | Independent · Day · 6th | Derby, East Midlands | — |
| 11 | Loughborough Grammar School Period 202122 | 44.4 | Independent · Boarding · 6th | Loughborough, East Midlands | — |
| 12 | Oakham School Period 202122 | 44.2 | Independent · Boarding · 6th | Oakham, East Midlands | — |
| 13 | Wellingborough School Period 202122 | 44.0 | Independent · Day · 6th | Wellingborough, East Midlands | — |
| 14 | Trent College Period 202122 | 44.0 | Independent · Boarding · 6th | Nottingham, East Midlands | — |
| 15 | Repton School Period 202122 | 43.8 | Independent · Boarding · 6th | Derby, East Midlands | — |
| 16 | Northampton High School GDST Period 202122 | 43.2 | Independent · Day · 6th | Unknown, East Midlands | — |
| 17 | Stamford Endowed Schools Period 202425 | 41.8 | Independent · Boarding · 6th | Lincolnshire, East Midlands | — |
| 18 | Derby Grammar School Period 202122 | 41.0 | Independent · Day · 6th | Unknown, East Midlands | — |
| 19 | Abbotsholme School Period 202122 | 40.8 | Independent · Boarding · 6th | Uttoxeter, East Midlands | — |
| 20 | Bosworth Independent School Period 202122 | 40.5 | Independent · Boarding · 6th | Unknown, East Midlands | — |
| 21 | St Crispin's School Period 202122 | 40.4 | Independent · Day | Leicester, East Midlands | — |
| 22 | Twycross House School Period 202324 | 40.0 | Independent · Day · 6th | Atherstone, East Midlands | Outstanding |
| 23 | Dixie Grammar School Period 202324 | 38.4 | Independent · Day · 6th | Nuneaton, East Midlands | — |
| 24 | Worksop College Period 202122 | 37.7 | Independent · Boarding · 6th | Worksop, East Midlands | — |
| 25 | Lincoln Minster School Period 202122 | 37.5 | Independent · Boarding · 6th | Lincoln, East Midlands | — |